" " Can Living in Deprived Areas and Depression Cause Premature Aging? – Wellness for Life " "
Wellness for Life
Advertisement
  • Home
  • News
  • Family Wellness
  • Health and Wellbeing
  • Mental Wellness
  • Contact us
No Result
View All Result
  • Home
  • News
  • Family Wellness
  • Health and Wellbeing
  • Mental Wellness
  • Contact us
No Result
View All Result
Wellness for Life
No Result
View All Result
Home News

Can Living in Deprived Areas and Depression Cause Premature Aging?

admin by admin
June 11, 2023
in News


Parminder Raina, a professor in the Department of Health Research Methods, Evidence, and Impact at McMaster University, led the research team, which included investigators from the Netherlands, Norway, and Switzerland (

).

“Our study used two DNA methylation-based estimators, known as epigenetic clocks, to examine aging at the cellular level and estimate the difference between chronological age and biological age,” said Divya Joshi, the study’s first author and a research associate in the Department of Health Research Methods, Evidence, and Impact at McMaster.

Advertisement

“Our findings showed that neighborhood deprivation and depressive symptoms were positively associated with the acceleration of the epigenetic age estimated using the DNAm GrimAge clock. This adds to the growing body of evidence that living in urban areas with higher levels of neighborhood deprivation and having depression symptoms are both associated with premature biological aging.”

Depression can Increase the Risk of Death

Depressive symptoms in the study were measured using a 10-item standardized depression scale. The researchers found an acceleration in the risk of death by one month for every point increase in the depressive symptom score. They theorized that emotional distress caused by depression may result in more biological wear and tear and dysregulation of physiological systems, which in turn could lead to premature aging.

The researchers assessed neighborhood material and social deprivation using two indices that were developed by the Canadian Urban Environmental Health Research Consortium (CANUE) based on the 2011 census.

Social deprivation reflects the presence of fewer social resources in the family and community, and material deprivation is an indicator of people’s inability to access goods and conveniences of modern life, such as adequate housing, nutritious food, a car, high-speed internet, or a neighborhood with recreational facilities.

The researchers found an increase in the risk of death by almost one year for those exposed to greater neighborhood deprivation compared to lower neighborhood deprivation.

The study did not find that neighborhood deprivation amplified the effect of depressive symptoms on epigenetic age acceleration.

“Our results showed that the effect of neighborhood deprivation on epigenetic age acceleration was similar regardless of depression symptoms, suggesting that depression influences epigenetic age acceleration through mechanisms unrelated to neighborhood deprivation,” Joshi said.

The research examined epigenetic data from 1,445 participants enrolled in the Canadian Longitudinal Study on Aging (CLSA), a research platform following more than 50,000 participants who were between the ages of 45 to 85 when recruited.

“Longitudinal studies, like the CLSA, are important to confirm associations like those found in this study,” said Raina, the study’s senior author and lead principal investigator of the CLSA.

“By following the same group of participants for 20 years, we will be able to determine whether epigenetic changes are stable or reversible over time. We will also gain insight into the mechanisms that are leading to accelerated epigenetic aging.”

Reference :

  1. Association of Neighborhood Deprivation and Depressive Symptoms With Epigenetic Age Acceleration: Evidence From the Canadian Longitudinal Study on Aging Get access Arrow – (https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glad118/7190263)

Source: Eurekalert



Source link

Tags: depressionEpigenetic clocksPremature agingSocial inequitiesUrban neighborhoods
Previous Post

Roundup: AI for predicting Alzheimer’s risk, training staff and more briefs

Next Post

Classic Aperol Spritz – Fit Foodie Finds

Next Post

Classic Aperol Spritz - Fit Foodie Finds

Recommended

Staying Healthy While Staying Open: The Polyamory Dilemma

January 6, 2023

Women’s health startup Iron Health launches with $4.5M

March 12, 2023

Don't miss it

Health and Wellbeing

Chicken Parmesan Quinoa Casserole – Fit Foodie Finds

September 22, 2023
Mental Wellness

How to Grow Your Mental Health Practice — Talkspace

September 22, 2023
News

Select Health, Mark Cuban team to lower prescription drug costs

September 22, 2023
Family Wellness

Keep Failing | Jim Daly

September 22, 2023
Family Wellness

The Best New York Fall Family Bucket List 2023

September 21, 2023
Family Wellness

As U.S. Syphilis Cases Rise, Those at the Epicenter Scramble

September 21, 2023

© Wellness For Life News Hubb All rights reserved.

Use of these names, logos, and brands does not imply endorsement unless specified. By using this site, you agree to the Privacy Policy and Terms & Conditions.

Navigate Site

  • Home
  • News
  • Family Wellness
  • Health and Wellbeing
  • Mental Wellness
  • Contact us

Newsletter Sign Up

Loading
No Result
View All Result
  • Home
  • News
  • Family Wellness
  • Health and Wellbeing
  • Mental Wellness
  • Contact us

© 2022 Wellness For Life News Hubb All rights reserved.